Optimization of black-box problems using Smolyak grids and polynomial approximations

Journal of Global Optimization 2018

C.A. Kieslich F. Boukouvala C.A. Floudas

A surrogate-based optimization method is presented, which aims to locate the global optimum of box-constrained problems using input–output data. The method starts with a global search of the n-dimensional space, using a Smolyak (Sparse) grid which is constructed using Chebyshev extrema…

ARGONAUT: AlgoRithms for Global Optimization of coNstrAined grey-box compUTational problems

Optimization Letters 2016

F. Boukouvala C.A. Floudas

The algorithmic framework ARGONAUT is presented for the global optimization of general constrained grey-box problems. ARGONAUT incorporates variable selection, bounds tightening and constrained sampling techniques, in order to develop accurate surrogate representations of unknown equations, which are globally optimized. ARGONAUT…

Data‐Driven Mathematical Modeling and Global Optimization Framework for Entire Petrochemical Planning Operations

AIChE Journal 2016

J. Lie X. Xiao F. Boukouvala C.A. Floudas B. Zhao G. Du S. Xu H. Liu

In this work we develop a novel modeling and global optimization-based planning formulation, which predicts product yields and properties for all of the production units within a highly integrated refinery-petrochemical complex. Distillation is modeled using swing-cut theory, while data-based nonlinear…

Global Optimization Advances in Mixed-Integer Nonlinear Programming, MINLP, and Constrained Derivative-Free Optimization, CDFO

European Journal of Operational Research 2015

F. Boukouvala R. Misener C.A. Floudas

This manuscript reviews recent advances in deterministic global optimization for Mixed-Integer Nonlinear Programming (MINLP), as well as Constrained Derivative-Free Optimization (CDFO). This work provides a comprehensive and detailed literature review in terms of significant theoretical contributions, algorithmic developments, software implementations…

An integrated approach for dynamic flowsheet modeling and sensitivity analysis of a continuous tablet manufacturing process

Computers & Chemical Engineering 2012

F. Boukouvala F.J. Muzzio M.G. Ierapetritou R. Ramachandran V. Niotis

Manufacturing of powder-based products is a focus of increasing research in the recent years. The main reason is the lack of predictive process models connecting process parameters and material properties to product quality attributes. Moreover, the trend towards continuous manufacturing…