A multi-scale framework for CO2 capture, utilization, and sequestration: CCUS and CCU

Computers and Chemical Engineering 2015

C.A. Floudas E. First F. Boukouvala M.M.F. Hasan

We present a multi-scale framework for the optimal design of CO2 capture, utilization, and sequestration (CCUS) supply chain network to minimize the cost while reducing stationary CO2 emissions in the United States. We also design a novel CO2 capture and…

Nationwide, Regional, and Statewide CO2 Capture, Utilization, and Sequestration Supply Chain Network Optimization

Industrial Engineering & Chemistry Research 2014

M.M.F. Hasan E. First F. Boukouvala C.A. Floudas

We design a CO2 Capture, Utilization, and Sequestration (CCUS) supply chain network with minimum cost to reduce stationary CO2 emissions and their adverse environmental impacts in the United States. While doing so, we consider simultaneous selection of source plants, capture…

Derivative-free optimization for expensive constrained problems using a novel expected improvement objective function

AIChE Journal 2014

F. Boukouvala M.G. Ierapetritou

In this work, an algorithm for the optimization of costly constrained systems is introduced. The proposed method combines advantages of global- and local-search algorithms with new concepts of feasibility space mapping, within a framework that aims to find global solutions…

Surrogate-based optimization of expensive flowsheet models for continuous pharmaceutical manufacturing

Journal of Pharmaceutical Information 2013

F. Boukouvala F.J. Muzzio M.G. Ierapetritou

Simulation-based optimization is a research area that is currently attracting a lot of attention in many industrial applications, where expensive simulators are used to approximate, design, and optimize real systems. Pharmaceuticals are typical examples of high-cost products which involve expensive…

Reduced order Discrete Element Method (DEM) modeling

Chemical Engineering Science 2013

F. Boukouvala F.J. Muzzio M.G. Ierapetritou Y. Gao

Reduced-order modeling (ROM) techniques are playing a very significant role in the recent literature bridging the gap between computationally expensive simulators and their application in optimization and control of distributed parameter systems. In modeling of solid-based processes, Discrete Element Method…