Data-driven Process Systems Engineering Lab
Research
Global Optimization of Grey-Box Constrained Models
2013 AIChE Annual Meeting in San Fransisco
November 05, 2013
Grey-box optimization methods have a wide range of applicability in various fields which rely on expensive simulations or solely input-output data [1]. Consequently, there has been great interest in the development of methods for the optimization of models for which…
Simulation-Based Derivative-Free Optimization for Computationally Expensive Functions
2012 AIChE Annual Meeting in Pittsburgh
October 31, 2012
Nowadays, the need to develop predictive models for complex processes along with advances in computational tools and capabilities have lead to the development of a plethora of detailed complex mathematical methods. However, as the complexity and level of detail increases,…
From Experimental Data to Building Integrated Dynamic Flowsheet Models for Pharmaceutical Processes
2012 AIChE Annual Conference in Pittsburgh
October 29, 2012
FDA harmonization guidelines [1] aim to promote building quality into design of pharmaceutical processes through mechanistic understanding of powder process behavior. Based on this paradigm, the industry is moving with a fast pace towards a model-based process and product design,…
Effect of Lubricant Mixing Time and Concentration, Compaction Speed and Compression Force On the Dissolution Profile of a Control Release Formulation
2012 AIChE Annual Conference in Pittsburgh
October 31, 2012
Dynamic Flowsheet Modeling Continuous Pharmaceutical Manufacturing
International Forum of Process Analytical Technology (IFPAC) in Baltimore
January 24, 2012
