Data-driven Process Systems Engineering Lab
Research
Dynamic Flowsheet Modeling and Sensitivity Analysis of Continuous Pharmaceutical Manufacturing
2011 AIChE Annual Meeting in Minneapolis
October 17, 2011
The main purpose of this work is to develop the necessary tools required to integrate, simulate and design continuous manufacturing systems for pharmaceutical powder based products. The development of a detailed simulation will enable (a) the optimization of the integrated…
Multivariate Analysis and Reduced Order Modeling Based On Discrete Element Method (DEM) Simulations for a Powder Blender
AIChE Annual Meeting in Minneapolis
October 20, 2011
In this work, a set of Discrete Element Method (DEM) simulations are performed based on a computer experimental design for the qualitative and quantitative characterization of a periodic section of a powder blender. Mixing of powders is a crucial operation…
Feasibility analysis of black- box processes using an adaptive sampling kriging-based method
European Symposium on Computer Aided Process Engineering in Halkidiki, Greece
June 01, 2011
Computer aided design and analysis of continuous pharmaceutical manufacturing processes
European Symposium on Computer Aided Process Engineering in Halkidiki, Greece
May 31, 2011
Application of Kriging for dynamic data- driven modeling of pharmaceutical processes
AIChE Annual Meeting in Salt Lake City
November 11, 2010
In emergent technologies it is very common that a functional form for the input-output relationships is unavailable and the process behavior is symbolically described using black-box models. This is the case for many pharmaceutical process operations, for which first-principles models…
